Pre-Exposure Prophylaxis (PrEP) is a single daily dose pill for HIV-negative individuals. People exposed to HIV can prevent contracting it with the assistance of PrEP.

To date, there are two FDA-approved medications for PrEP, Truvada® the original PrEP approved in 2012, and now Descovy®, which was approved in 2019. Studies have shown that PrEP reduces the risk of getting HIV from sex by about 99% when taken daily.